Postoperative Pain and Incidence of Extrusion Following the Use of Two Intra-Canal Medications in Retreatment of Single Rooted Teeth A Prospective Clinical Trial

Document Type : Original Article

Authors

1 Department of Endodontics, Faculty of Dentistry, Minia University, El-Minia, Egypt

2 Department of Endodontics, Faculty of Dentistry, Minia University, El Minia , Egypt

10.21608/aadj.2025.372929.1209

Abstract

 Aim:  Compare the postoperative pain intensity and flare up and extrusion incidence 
of two intracanal medications in retreatment of single rooted teeth in a double blinded 
prospective clinical trial. Subjects and methods: Thirty healthy patients; diagnosed 
with asymptomatic apical periodontitis; equally and randomly divided into two groups 
according to the applied intracanal medication (Metapex (MP) group and Bio-C Temp 
(BC) group) after complete removal of the old obturation material. Postoperative 
Pain intensity were documented on visual analog scale (VAS) 12 hours then every 
24h for 7 days. Incidence of apical extrusion and flare ups were also recorded.  
Results: All pairwise comparisons between time points intragroup were significant at 
p value ≤ (0.004), demonstrating a clear pattern of progressive pain reduction over 
the observation period.  However, intergroup comparison at any of the measured time 
points and flare up incidence showed no significance. MP group showed significantly 
higher extrusion rate than did BC group with p value = (0.005). In the MP group, 8 
participants (53.3%) experienced extrusion compared to only 1 participant (6.7%) in 
the BT group. Conclusion: Bioceramic based intracanal medicament is as effective 
and safe as calcium hydroxide in reducing postoperative pain and flare up incidence 
in retreatment cases. However, it is significantly lower regarding extrusion incidence.  

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