The Remineralizing and Desensitizing Effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) Versus Fluoride Cream Application Following the Use of Lumacool (Teeth Whitening Pen) on Premolars: An Ex-Vivo Trial

Sharaf, Mohamed Fouad Saad; Bashir, Maha Hassan; Helal, Mohamed Elsayed Mohamed; Mubarak, Rabab Tawfik

doi:10.21608/aadj.2024.317406.1189

The Remineralizing and Desensitizing Effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) Versus Fluoride Cream Application Following the Use of Lumacool (Teeth Whitening Pen) on Premolars: An Ex-Vivo Trial

Document Type : Original Article

Authors

¹ Oral Biology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt .

² Oral Biology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt

10.21608/aadj.2024.317406.1189

Abstract

Aim: This study sought to compare the remineralizing and desensitizing
capabilities of case in phospho-peptide-amorphous calcium phosphate (CPP-ACP) and
f
luoride cream when applied after Lumacool (a teeth whitening pen) on premolars.
Subjects and methods: Fifty-six stained sound human premolars were divided
into four equal groups and bleached with different agents. Patient tooth sensitivity
was assessed using the Visual Analogue Scale (VAS) at 1, 7, 14, and 28 days post
application. Teeth were subsequently extracted and prepared for scanning electron
microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and Vickers micro
hardness testing. Morphological analysis was conducted using SEM, and statistical
analysis of paired (matched) data was performed with the Wilcoxon signed rank test.
Results: highest mean values were observed at day 28 in Groups 3 and 4 (6.14 ± 1.86 and
6.14 ± 2.04, respectively), while the lowest was in Group 1 at day 1 (0.43 ± 0.54). SEM
examination of the enamel surface revealed surface irregularities, cracks, and scratches
in the hydrogen peroxide groups, contrasting with the relatively smooth surface in the
placebo group. Enamel micro-hardness significantly decreased (p < 0.05) in all groups,
with Group 2 and Group 4 being the most affected (p = 0.018). Group 1 showed a
moderate decrease (p = 0.043), while Group 3 exhibited minimal change (p = 0.866).
Conclusion: Hydrogen peroxide is effective for bleaching. Calcium supplementation
improves tooth properties and reduces sensitivity. Fluoride is effective for desensitization.
Calcium and fluoride combined offer limited benefits compared to individual use.

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